The United States Global Climate Change Research Program’s 2016 report, “The Impacts of Climate Change on Human Health in the United States: A Scientific Assessment,” summarizes that climate change is a significant threat to the health of the American people (USGCRP 2016). The U.S. Centers for Disease Control and Prevention (CDC) developed the Building Resilience against Climate Effects (BRACE) framework to support its Climate-Ready States and Cities Initiative to help decision makers prepare for the public health impacts of a changing climate. The New Jersey Climate Adaptation Alliance (NJCAA), which is facilitated by Rutgers University, has developed this Climate and Health Profile Report in accordance with the BRACE Step 1 guidelines (CDC 2014) and in consultation with its Climate Change and Public Health Working Group. The report provides a framework to utilize existing data, epidemiological studies, and models of weather patterns to assess the future public health burden from climate risks and to lay the foundation for developing best practices for adaptation.